Continuation of General Chemistry I. Chemical
equilibrium, kinetics, thermochemistry,
thermodynamics, electrochemistry, inorganic
chemistry. Weekly laboratory exercises
emphasizing quantitative techniques that
complement the lecture material. Lecture,
discussion, laboratory.
Select topics in biochemistry and molecular
biology. Students attend seminars of invited
outside researchers and have the option to prepare
an oral seminar based on their own research or on
a critical analysis of a relevant research
publication.
Chemistry of aldehydes and ketones (reactions at
and adjacent to the carbonyl group, enolization,
conjugate addition, oxidation, reduction).
Lecture, conference, laboratory. Synthesis,
chemistry of carboxylic acids and derivatives (pKa
of acids, nucleophilic substitution of
derivatives, acyl chlorides, esters, amides,
anhydrides, nitriles). Carbohydrates
(stereochemistry, aldoketoses, aldopentoses,
aldohexoses, ketosugars, derivatives, furanose and
pyranose forms, reducing and nonreducing sugars,
disaccharides and polysaccharides); fats and oils;
aromatic hydrocarbons (benzene, resonance and
molecular orbital approaches, electrophilic and
nucleophilic aromatic substitution); aromatic
nitrogen and oxygen chemistry (diazotization,
synthesis); chemistry of amines, amino acids,
peptides, proteins, DNA; other topics. Lecture,
discussion, laboratory.
Laboratory course to demonstrate the principles of
physical and analytical chemistry and to develop
research aptitude in chemistry. Investigation of
thermochemistry, equilibria, electrochemistry,
kinetics, spectroscopy, photochemistry, and
material science. Techniques used may include
fluorescence, UV-visible, IR, Raman, NMR, and mass
spectroscopies; diffraction; and computational
chemistry. Lecture, laboratory, oral
presentations.
Modern concepts of inorganic and transition-metal
chemistry with emphasis on bonding, structure,
thermodynamics, kinetics and mechanisms, and
periodic and family relationships. Atomic
structure, theories of bonding, symmetry,
molecular shapes (point groups), crystal
geometries, acid-base theories, survey of familiar
elements, boron hydrides, solid-state materials,
nomenclature, crystal field theory, molecular
orbital theory, isomerism, geometries, magnetic
and optical phenomena, spectra, synthetic methods,
organometallic compounds, cage structures,
clusters, lanthanides, actinides.